Figure 9. Self-assembly of gold NC-polypeptide hybrid materials via cystine-thiol cross-linkages with a maleimido-tris(benzamide)phosphine passivated NC surface (left). The polypeptide components, a helical peptide (middle) and the protein pI3K SH3 (right), each contain two cystine residues and thus couple to two NCs. Transmission electron microscopy confirms that the expected NC-NC geometries are achieved. (Due to their significantly lower electron density, the polypeptide chain is not visible.) [Major and Strouse, unpublished.] Phone: (805) 893-2001 | Email: pat@ipos.ucsb.edu | UCSB Website